Month: October 2022

IQCC Forum: Autumn edition 2022

Last Thursday took place the Autumn edition of the IQCC Forum, a quarterly meeting-place where high-quality science is discussed. The IQCC Forum gives the opportunity for PhD and postdoc members of the IQCC to present their work to a select group of critical researchers, enhancing intra-IQCC collaborations and promoting knowledge exchange within the institute. This

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PhD defense Ernest Ubasart

Next Friday will be the defense of the doctoral thesis of Ernest Ubasart Clarà, titled “Synthesis and applications of large supramolecular nanocapsules: Matryoshka-type masks, higher fullerene C84 purification and stabilization of metallic clusters and sub-namoparticles”, supervised by Xavi Ribas from IQCC. Place: Aula Magna – Facultat de Ciències Date: October 28, 2022 Time: 10.30h We wish him good luck

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Selective Biocatalytic N-Methylation of Unsaturated Heterocycles

Methods for regioselective N-methylation and -alkylation of unsaturated heterocycles with “off the shelf” reagents are highly sought-after. This reaction could drastically simplify synthesis of privileged bioactive molecules. Here we report engineered and natural methyltransferases for challenging N-(m)ethylation of heterocycles, including benzimidazoles, benzotriazoles, imidazoles and indazoles. The reactions are performed through a cyclic enzyme cascade that consists of

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