Cover Nat. Synth. on Biocatalytic desymmetrization for synthesis of chiral enones using flavoenzymes
The Nature Synthesis journal features on its front cover of the November 2024 issue the research article “Biocatalytic desymmetrization for synthesis of chiral enones using flavoenzymes” by Dr. Garcia-Borràs in collaboration with Prof. Zhen Liu’s group. Chiral enones are produced, using flavin-dependent ene-reductases, through a desymmetrization approach. Enzymatic desaturation and reduction processes enable the synthesis of either enantiomer of the enone products from cyclohexanone or cyclohexadienone substrates.
The corresponding paper was published recently:
Qing-Qing Zeng, Qian-Yi Zhou, Carla Calvó-Tusell, Shuang-Yu Dai, Xiang Zhao, Marc Garcia-Borràs, Zhen Liu
Biocatalytic desymmetrization for synthesis of chiral enones using flavoenzymes
Nat. Synth, 2024, 3, 1340-1348
DOI: 10.1038/s44160-024-00596-4
Girona, November 28th, 2024
For more info: ges.iqcc@udg.edu