Anna Rogans and Anna Pla-Quintana were invited recently to write a highlight in the News & Views section of Nature Synthesis to describe the significance of Rh-catalyzed cycloaddition reactions, as reported by Uchiyama, Tanaka and co-workers in their paper in Nature Synthesis.
Dr. Roglans and Dr. Pla-Quintana take advantage of their expertise in transition-metal catalysed [2+2+2] cycloaddition reactions of unsaturated substrates to summarise and highlight the work done by this Japanese research group. We note that this process is a powerful tool to synthesize a wide range of six-membered rings with high levels of diversity and complexity in a single reaction step with perfect atom economy.
The highlight was recently reported in Nature Synthesis:
A. Pla-Quintana and A. Roglans
“Cyclotrimerization takes orders from rhodium”
Nat. Synth 2022, 1, 337-338
DOI: 10.1038/s44160-022-00059-8
Girona, June 16, 2022
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