Today Sílvia Osuna received the Premio Lilly Joven de Investigación 2019 at the headquarters of Lilly in Madrid, where she also delivered her award-ceremony talk “Computational enzyme evolution”. She has won the award, as already announced earlier this year, for her outstanding scientific career on enzyme design, fullerenes, and carbon materials. The Lilly Prize for Young Investigators distinguishes annually one excellent young talented Spanish researcher (<40 years) for their scientific quality and professional career path. This is the second time that this honour has been bestowed on a IQCC researcher: in 2016 Anna Company received the award for the first time.